Recombinant Human monoclonal antibody expressed in CHO binding to Human IL21R. PF-05230900 is a fully human monoclonal anti-IL-21 receptor (IL-21R) antibody, has a prolonged PD effect measured by IL-21R occupancy; was highly immunogenic after single dose administration and has PK properties with rapid clearance and low bioavailability.
Figure 1 Anti-Human IL21R Recombinant Antibody (TAB- 416CL) in WB
Western blot analysis of TAB- 416CL was performed by loading human IL21R protein onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB- 416CL and a HRP goat anti-IgG (H+L) was used as the secondary antibody (1: 3000). Chemiluminescent detection was performed.
Figure 2 Anti-Human IL21R Recombinant Antibody (TAB- 416CL) in DB
Dot Blot analysis of TAB- 416CL was performed by coating with human IL21R protein (His tag).
TAB- 416CL incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-IgG (H+L) secondary antibody (1: 3000)
NC: Negative control, PC: Positive control
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-583LC | Rat Anti-IL21R Recombinant Antibody (TAB-583LC) | ELISA, WB | Rat IgG |
TAB-583LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-583LC-S(P)) | ELISA, WB | Rat scFv |
TAB-584LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-584LC-S(P)) | ELISA, WB | Rat scFv |
TAB-583LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-583LC-F(E)) | ELISA, WB | Rat Fab |
TAB-584LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-584LC-F(E)) | ELISA, WB | Rat Fab |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-416CL, RRID: AB_3111928)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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